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ADAM PROTEINS
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DeCS
Descriptor
English
:
ADAM Proteins
Descriptor
Spanish
:
Proteínas ADAM
Descriptor
Portuguese
:
Proteínas ADAM
Tree Number:
D08.811.277.656.675.374.102
D09.400.430.500
D12.776.395.033
Definition
English
:
A
family
of membrane-anchored
glycoproteins
that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane
proteins
and the release of their extracellular domain.
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50583
Unique Identifier:
D051722
Occurrence in VHL
:
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DeCS
CID-10
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