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ANTHRAMYCIN
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DeCS
Descriptor
English
:
Anthramycin
Descriptor
Spanish
:
Antramicina
Descriptor
Portuguese
:
Antramicina
Tree Number:
D03.438.079.080.070.050
D03.494.060
Definition
English
:
A broad-spectrum spectrum antineoplastic antibiotic isolated from
Streptomyces
refuineus var. thermotolerans. It has low
toxicity
, some activity against
Trichomonas
and Endamoeba, and inhibits
RNA
and
DNA
synthesis. It binds irreversibly to
DNA.
Pharmacological Action:
Antibiotics, Antineoplastic
History Note
English
:
91(75); was see under BENZODIAZEPINONES 1975-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
891
Unique Identifier:
D000876
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS