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ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC
Descriptors Found:
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DeCS
Descriptor
English
:
Antibodies, Antineutrophil Cytoplasmic
Descriptor
Spanish
:
Anticuerpos Citoplasmáticos Antineutrófilo
Descriptor
Portuguese
:
Anticorpos Anticitoplasma de Neutrófilos
Synonyms
English
:
c-ANCA
p-ANCA
Antineutrophil Cytoplasmic Antibodies
ANCA
Tree Number:
D12.776.124.486.485.114.323.190
D12.776.124.790.651.114.323.190
D12.776.377.715.548.114.323.190
D23.101.050
Definition
English
:
Autoantibodies
directed against cytoplasmic constituents of POLYMORPHONUCLEAR
LEUKOCYTES
and/or
MONOCYTES
. They are used as specific markers for
WEGENER GRANULOMATOSIS
and other diseases, though their pathophysiological
role
is not clear. ANCA are routinely detected by indirect immunofluorescence with three different patterns: c-ANCA (cytoplasmic), p-ANCA (perinuclear), and atypical ANCA.
Indexing Annotation
English
:
do not coordinate with
ANTIBODY FORMATION
for /biosyn;
Pharmacological Action:
Immunologic Factors
History Note
English
:
97; was C-ANCA (NM) 1991-96
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33077
Unique Identifier:
D019268
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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