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ARGININE CARBOXYPEPTIDASE
Descriptors Found:
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DeCS
Descriptor
English
:
Carboxypeptidase U
Descriptor
Spanish
:
Carboxipeptidasa U
Descriptor
Portuguese
:
Carboxipeptidase U
Synonyms
English
:
Arginine Carboxypeptidase
Thrombin-Activatable Fibrinolysis Inhibitor
Tree Number:
D08.811.277.656.350.245.224
D08.811.277.656.350.555.300
D08.811.277.656.675.555.300
D08.811.277.656.837.186
Definition
English
:
A metallocarboxypeptidase that removes C-terminal
lysine
and
arginine
from biologically active
peptides
and
proteins
thereby regulating their activity. It is a
zinc
enzyme with no preference shown for
lysine
over
arginine
. Pro-carboxypeptidase U in human
plasma
is activated by
thrombin
or plasmin during clotting to form the unstable
carboxypeptidase U.
History Note
English
:
2002; use CARBOXYPEPTIDASE U (NM) 1994-2001 and LYSINE CARBOXYPEPTIDASE 1997-2001
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
36082
Unique Identifier:
D025901
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS