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ARYLSULFATASE B
Descriptors Found:
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DeCS
Descriptor
English
:
N-Acetylgalactosamine-4-Sulfatase
Descriptor
Spanish
:
N-Acetilgalactosamina-4-Sulfatasa
Descriptor
Portuguese
:
N-Acetilgalactosamina-4-Sulfatase
Synonyms
English
:
Arylsulfatase B
Tree Number:
D08.811.277.352.827.070.060
D08.811.277.352.827.180.175.060
Definition
English
:
An arylsulfatase that catalyzes the
hydrolysis
of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of
chondroitin
sulfate and
dermatan sulfate
. A deficiency of this enzyme is responsible for the inherited lysosomal
disease
, Maroteaux-Lamy
syndrome
(
MUCOPOLYSACCHARIDOSIS VI
). EC 3.1.6.12.
Entry Combination - descr/qualif
English
:
N-Acetylgalactosamine-4-Sulfatase
/
deficiency
use
Mucopolysaccharidosis VI
History Note
English
:
99; for ARYLSULFATASE B use CHONDRO-4-SULFATASE 1975-98; use N-ACETYLGALACTOSAMINE-4-SULFATASE (NM) 1988-98
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33824
Unique Identifier:
D020051
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS