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CSF-1 RECEPTOR
Descriptors Found:
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DeCS
Descriptor
English
:
Receptor, Macrophage Colony-Stimulating Factor
Descriptor
Spanish
:
Receptor de Factor Estimulante de Colonias de Macrófagos
Descriptor
Portuguese
:
Receptor de Fator Estimulador de Colônias de Macrófagos
Synonyms
English
:
c-fms Protein
fms Proto-Oncogene Protein
Proto-Oncogene Protein fms
Antigens, CD115
CD115 Antigens
CSF-1 Receptor
Receptor, CSF-1
Tree Number:
D08.811.913.696.620.682.725.400.500
D12.776.543.750.060.492
D12.776.543.750.705.852.150.150
D12.776.543.750.750.400.200.200
D12.776.624.664.700.800
D23.050.301.264.035.597
D23.101.100.110.597
Definition
English
:
A receptor for
MACROPHAGE COLONY-STIMULATING FACTOR
encoded by the c-fms proto-oncogene (
GENES
, FMS). It contains an intrinsic protein-tyrosine kinase activity. When activated the receptor undergoes autophosphorylation,
phosphorylation
of down-stream signaling molecules and rapid
down-regulation.
Indexing Annotation
English
:
DF: RECEPT MCSF
See Related
English
:
Genes, fms
History Note
English
:
2000(1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30890
Unique Identifier:
D016186
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS