Search on: COMPOUND Q 
Descriptors Found: 1
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Descriptor English:   Trichosanthin 
Descriptor Spanish:   Tricosantina 
Descriptor Portuguese:   Tricosantina 
Synonyms English:   alpha-Trichosanthin
Compound Q  
Tree Number:   D12.776.765.710.500.500
Definition English:   Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS. 
Indexing Annotation English:   /drug eff /ultrastruct permitted
Pharmacological Action:   Abortifacient Agents, Nonsteroidal
Anti-HIV Agents
Antineoplastic Agents, Phytogenic
 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   24902 
Unique Identifier:   D015978 

Occurrence in VHL:
 

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