Search on: CORE BINDING FACTOR ALPHA 1 SUBUNIT 
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Descriptor English:   Core Binding Factor Alpha 1 Subunit 
Descriptor Spanish:   Subunidad alfa 1 del Factor de Unión al Sitio Principal 
Descriptor Portuguese:   Subunidade alfa 1 de Fator de Ligação ao Core 
Tree Number:   D12.776.930.155.200.100
Definition English:   A transcription factor that dimerizes with CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain and is involved in genetic regulation of skeletal development and CELL DIFFERENTIATION. 
Indexing Annotation English:   see SCR for organism-specific terms
History Note English:   2006(1997) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   51176 
Unique Identifier:   D050659 

Occurrence in VHL:
 

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