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CRK-ASSOCIATED SUBSTRATE PROTEIN
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DeCS
Descriptor
English
:
Crk-Associated Substrate Protein
Descriptor
Spanish
:
Proteína Sustrato Asociada a CrK
Descriptor
Portuguese
:
Proteína Substrato Associada a Crk
Tree Number:
D12.644.360.024.295
D12.776.157.057.022
D12.776.476.024.374
D12.776.744.425
Definition
English
:
Crk-associated substrate was originally identified as a highly phosphorylated 130 kDa protein that associates with ONCOGENE PROTEIN CRK and ONCOGENE PROTEIN SRC. It is a signal transducing adaptor protein that undergoes
tyrosine
PHOSPHORYLATION
in signaling pathways that regulate CELL
MIGRATION
and
CELL PROLIFERATION.
History Note
English
:
2006(2004)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50765
Unique Identifier:
D050719
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS