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GLUTARYL-COA DEHYDROGENASE
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DeCS
Descriptor
English
:
Glutaryl-CoA Dehydrogenase
Descriptor
Spanish
:
Glutaril-CoA Deshidrogenasa
Descriptor
Portuguese
:
Glutaril-CoA Desidrogenase
Tree Number:
D08.811.682.660.425
Definition
English
:
A flavoprotein enzyme that is responsible for the catabolism of
LYSINE
;
HYDROXYLYSINE
; and
TRYPTOPHAN
. It catalyzes the
oxidation
of GLUTARYL-CoA to crotonoyl-CoA using FAD as a cofactor. Glutaric aciduria type I is an inborn error of
metabolism
due to the deficiency of
glutaryl-CoA dehydrogenase.
History Note
English
:
2006(1973)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50627
Unique Identifier:
D050770
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS