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Descriptor English:   ISCOMs 
Descriptor Spanish:   ISCOMs 
Descriptor Portuguese:   ISCOMs 
Synonyms English:   Immunostimulating Complexes  
Tree Number:   D20.215.894.860.449
Definition English:   A formulation for presenting an antigen to induce specific immunologic responses. It consists of an assembly of antigens in multimeric form. The assembly is attached to a matrix with a built-in adjuvant, saponin. ISCOMs induce strong serum antibody responses, and are used as highly immunogenic forms of subunit vaccines. 
Indexing Annotation English:   coord IM with specific type of vaccine (IM or NIM); DF: ISCOM
Pharmacological Action:   Adjuvants, Immunologic
 
See Related English:   Saponins
 
History Note English:   92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PD pharmacology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30027 
Unique Identifier:   D016882 

Occurrence in VHL:
 

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