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INSULIN-LIKE GROWTH FACTOR II
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DeCS
Descriptor
English
:
Insulin-Like Growth Factor II
Descriptor
Spanish
:
Factor II del Crecimiento Similar a la Insulina
Descriptor
Portuguese
:
Fator de Crescimento Insulin-Like II
Synonyms
English
:
IGF-II
Multiplication-Stimulating Activity
Somatomedin MSA
Tree Number:
D12.644.276.937.420
D12.776.124.862.425
D12.776.467.937.420
D23.529.937.420
Definition
English
:
A well-characterized neutral peptide believed to be secreted by the
LIVER
and to circulate in the
BLOOD
. It has growth-regulating, insulin-like and mitogenic activities. The
growth
factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal
growth
factor in contrast to
INSULIN-LIKE GROWTH FACTOR I
, which is a major
growth
factor in adults.
See Related
English
:
Receptor, IGF Type 1
Receptor, IGF Type 2
History Note
English
:
1991(1986)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22313
Unique Identifier:
D007335
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS