Search on: INSULINASE 
Descriptors Found: 1
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Descriptor English:   Insulysin 
Descriptor Spanish:   Insulisina 
Descriptor Portuguese:   Insulisina 
Synonyms English:   Insulinase  
Tree Number:   D08.811.277.656.300.480.300
D08.811.277.656.675.374.300
Definition English:   An enzyme the catalyzes the degradation of insulin, glucagon and other polypeptides. It is inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and by thiol-blocking reagents such as N-ethylmaleimide, but not phosphoramidon. (Eur J Biochem 1994;223:1-5) EC 3.4.24.56. 
History Note English:   97; was INSULINASE 1963-96 (see under PEPTIDE HYDROLASES 1975-90, see under ENDOPEPTIDASES 1963-74) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   7509 
Unique Identifier:   D007339 

Occurrence in VHL:
 

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