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LACTOSYLCERAMIDES
Descriptors Found:
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DeCS
Descriptor
English
:
Lactosylceramides
Descriptor
Spanish
:
Lactosilceramidos
Descriptor
Portuguese
:
Lactosilceramidas
Synonyms
English
:
Lactosyl Ceramides
Tree Number:
D02.065.313.612
D09.400.410.420.525.200.612
D10.390.470.675.200.612
D10.570.877.360.612.200.612
Definition
English
:
Glycosphingolipids
which contain as their polar
head
group a
lactose
moiety bound in glycosidic linkage to the hydroxyl group of ceramide. Their accumulation in tissue, due to a defect in lactosylceramide
beta-galactosidase
, is the cause of lactosylceramidosis.
Indexing Annotation
English
:
/biosyn /physiol permitted
History Note
English
:
91(79); was see under GLYCOSPHINGOLIPIDS 1979-90
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
7968
Unique Identifier:
D007790
Occurrence in VHL
:
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DeCS
CID-10
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