Search on: LYSINE 2-OXOGLUTARATE DIOXYGENASE 
Descriptors Found: 1
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Descriptor English:   Procollagen-Lysine, 2-Oxoglutarate 5-Dioxygenase 
Descriptor Spanish:   Procolágeno-Lisina 2-Oxoglutarato 5-Dioxigenasa 
Descriptor Portuguese:   Pró-colágeno-Lisina 2-Oxoglutarato 5-Dioxigenase 
Synonyms English:   Lysine 2-Oxoglutarate Dioxygenase
Protocollagen Lysyl Hydroxylase
Lysine Hydroxylase  
Tree Number:   D08.811.682.690.708.660
Definition English:   A mixed-function oxygenase that catalyzes the hydroxylation of peptidyllysine, usually in protocollagen, to peptidylhydroxylysine. The enzyme utilizes molecular oxygen with concomitant oxidative decarboxylation of the cosubstrate 2-oxoglutarate to succinate. EC 1.14.11.4. 
Indexing Annotation English:   DF: note short X ref
History Note English:   92; was LYSINE HYDROXYLASE 1977-91 (see under HYDROXYLASES 1977-90) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30382 
Unique Identifier:   D008240 

Occurrence in VHL:
 

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