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NERVE GROWTH CONE MEMBRANE PROTEIN GAP-43
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DeCS
Descriptor
English
:
GAP-43 Protein
Descriptor
Spanish
:
Proteína GAP-43
Descriptor
Portuguese
:
Proteína GAP-43
Synonyms
English
:
B-50 Protein
Nerve Growth Cone Membrane Protein GAP-43
GAP-43
Neuromodulin
Growth-Associated Protein 43
Tree Number:
D12.776.395.550.400
D12.776.543.550.400
D12.776.641.400
Definition
English
:
A nervous tissue specific protein which is highly expressed in
NEURONS
during development and
NERVE REGENERATION
. It has been implicated in neurite outgrowth,
long-term potentiation
,
SIGNAL TRANSDUCTION
, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of
PROTEIN KINASE C.
History Note
English
:
98; use GAP-43 PROTEIN (NM) 1986-97
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
33491
Unique Identifier:
D019922
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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