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DeCS
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Descriptor English:
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Nonsuppressible Insulin-Like Activity
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Descriptor Spanish:
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Actividad Similar a la Insulina no Suprimible
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Descriptor Portuguese:
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Atividade Insulin-Like não Suprimível
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Synonyms English:
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NSILA
NSILA-P
NSILA-S
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Tree Number:
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D12.776.124.862.575
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Definition English:
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A blood protein (NSILA) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of Cohn fraction III, 10% of the activity is found in the supernatant (NSILA-S) and the remaining activity in the precipitate (NSILA-P). The latter is a large molecular compound, much less stable than the soluble fraction. NSILA-S is a more potent growth factor than insulin and exhibits sulfation activity. |
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Indexing Annotation English:
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note category; a blood protein mimicking blood insulin
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History Note English:
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77
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Allowable Qualifiers English:
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Record Number:
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22249
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Unique Identifier:
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D009632
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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