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PIAS1 PROTEIN INHIBITOR OF ACTIVATED STAT
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DeCS
Descriptor
English
:
Protein Inhibitors of Activated STAT
Descriptor
Spanish
:
Proteínas Inhibidoras de STAT Activados
Descriptor
Portuguese
:
Proteínas Inibidoras de STAT Ativados
Synonyms
English
:
PIAS1 Protein Inhibitor of Activated STAT
Tree Number:
D12.644.360.024.311
D12.776.157.057.124
D12.776.476.024.405
Definition
English
:
A
family
of structurally related
proteins
that are constitutively expressed and that negatively regulate cytokine-mediated
SIGNAL TRANSDUCTION
PATHWAYS. PIAS
proteins
inhibit the activity of signal
transducers
and activators of transcription.
History Note
English
:
2006(1998)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50781
Unique Identifier:
D050828
Occurrence in VHL
:
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