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RECEPTORS, PDGF
Descriptors Found:
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DeCS
Descriptor
English
:
Receptors, Platelet-Derived Growth Factor
Descriptor
Spanish
:
Receptores del Factor de Crecimiento Derivado de Plaquetas
Descriptor
Portuguese
:
Receptores do Fator de Crescimento Derivado de Plaquetas
Synonyms
English
:
Platelet-Derived Growth Factor Receptors
PDGF Receptors
Receptors, PDGF
Tree Number:
D08.811.913.696.620.682.725.400.900
D12.776.543.750.060.625
D12.776.543.750.750.400.630
Definition
English
:
Specific receptors on cell
membranes
that react with
PLATELET-DERIVED GROWTH FACTOR
, its analogs, or antagonists. The alpha PDGF receptor (RECEPTOR,
PLATELET-DERIVED GROWTH FACTOR
ALPHA) and the beta PDGF receptor (RECEPTOR,
PLATELET-DERIVED GROWTH FACTOR
BETA) are the two principle types of PDGF receptors. Activation of the protein-tyrosine kinase activity of the receptors occurs by ligand-induced
dimerization
or heterodimerization of PDGF receptor types.
Indexing Annotation
English
:
DF: RECEPT PDGF
See Related
English
:
Platelet-Derived Growth Factor
History Note
English
:
93; was PLATELET-DERIVED GROWTH FACTOR RECEPTOR (NM) 1982-92; PLATELET DERIVED GROWTH FACTOR RECEPTOR-KINASE was NM 1989-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
30547
Unique Identifier:
D017479
Occurrence in VHL
:
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