Search on: RIBONUCLEOSIDE DIPHOSPHATE REDUCTASE 
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Descriptor English:   Ribonucleoside Diphosphate Reductase 
Descriptor Spanish:   Ribonucleósido Difosfato Reductasa 
Descriptor Portuguese:   Ribonucleosídeo Difosfato Redutase 
Tree Number:   D08.811.682.810.567
Definition English:   An enzyme of the oxidoreductase class that catalyzes the formation of 2'-deoxyribonucleotides from the corresponding ribonucleotides using NADPH as the ultimate electron donor. The deoxyribonucleoside diphosphates are used in DNA synthesis. (From Dorland, 27th ed) EC 1.17.4.1. 
History Note English:   91(75); was see under RIBONUCLEOTIDE REDUCTASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   12671 
Unique Identifier:   D012262 

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