Search on: SRP (SIGNAL RECOGNITION PARTICLE) 
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Descriptor English:   Signal Recognition Particle 
Descriptor Spanish:   Partícula de Reconocimiento de Señal 
Descriptor Portuguese:   Partícula de Reconhecimento de Sinal 
Synonyms English:   SRP (Signal Recognition Particle)  
Tree Number:   D12.776.157.725.500.750.800
D12.776.664.962.500.750.800
Definition English:   A cytosolic ribonucleoprotein complex that acts to induce elongation arrest of nascent presecretory and membrane proteins until the ribosome becomes associated with the rough endoplasmic reticulum. It consists of a 7S RNA and at least six polypeptide subunits (relative molecular masses 9, 14, 19, 54, 68, and 72K). 
Indexing Annotation English:   DF: note short X ref
See Related English:   Protein Sorting Signals
 
History Note English:   94; was SIGNAL RECOGNITION PARTICLE (NM) 1985-93 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   31046 
Unique Identifier:   D018271 

Occurrence in VHL:
 

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