Search on: SULFONAMIDES 
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Descriptor English:   Sulfonamides 
Descriptor Spanish:   Sulfonamidas 
Descriptor Portuguese:   Sulfonamidas 
Tree Number:   D02.065.884
D02.886.590.700
Definition English:   A group of compounds that contain the structure SO2NH2. Members of this group, also known as sulfa drugs, are derivatives of sulfanilamide, which competitively inhibit folic acid synthesis in microorganisms, and are bacteriostatic. They have been largely supplanted by more effective and less toxic antibiotics. (From Dorland, 28th ed) 
History Note English:   SULFONAMIDE MIXTURES was heading 1963-79 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DU diagnostic use
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   13837 
Unique Identifier:   D013449 

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