Search on: TOXINS, TARGETED 
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Descriptor English:   Immunotoxins 
Descriptor Spanish:   Inmunotoxinas 
Descriptor Portuguese:   Imunotoxinas 
Synonyms English:   Antibody-Toxin Conjugates
Antibody-Toxin Hybrids
Cytotoxin-Antibody Conjugates
Targeted Toxins
Toxin-Antibody Conjugates
Toxin-Antibody Hybrids
Toxin Carriers
Toxin Conjugates
Toxins, Targeted
Chimeric Toxins
Toxins, Chimeric  
Tree Number:   D12.776.124.486.485.114.580.450
D12.776.124.790.651.114.580.450
D12.776.377.715.548.114.580.450
D27.888.569.271
Definition English:   Semisynthetic conjugates of various toxic molecules, including RADIOACTIVE ISOTOPES and bacterial or plant toxins, with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; and ANTIGENS. The antitumor or antiviral immune substance carries the toxin to the tumor or infected cell where the toxin exerts its poisonous effect. 
Indexing Annotation English:   coordinate IM with specific toxin (IM) + specific immune substance (NIM)
Pharmacological Action:   Immunologic Factors
 
History Note English:   90; was ANTIBODY-TOXIN CONJUGATES 1987-89 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BL blood
CF cerebrospinal fluid CH chemistry
CL classification CT contraindications
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   28229 
Unique Identifier:   D000922 

Occurrence in VHL:
 

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