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TRANSFORMING GROWTH FACTOR BETA3
Descriptors Found:
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DeCS
Descriptor
English
:
Transforming Growth Factor beta3
Descriptor
Spanish
:
Factor de Crecimiento Transformador beta3
Descriptor
Portuguese
:
Fator de Crescimento Transformador beta3
Synonyms
English
:
TGF-beta3
Tree Number:
D12.644.276.374.687.300
D12.644.276.954.800.720.300
D12.644.276.963.720.300
D12.776.467.374.687.300
D12.776.467.942.800.720.300
D12.776.467.960.720.300
D23.529.942.800.720.300
D23.529.960.720.300
Definition
English
:
A TGF-beta subtype that plays
role
in regulating epithelial-mesenchymal interaction during
embryonic development
. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The
association
of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
History Note
English
:
2007(2000)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52287
Unique Identifier:
D053782
Occurrence in VHL
:
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CID-10
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