Search on: TRYPTOPHAN INDOLE-LYASE 
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Descriptor English:   Tryptophanase 
Descriptor Spanish:   Triptofanasa 
Descriptor Portuguese:   Triptofanase 
Synonyms English:   Tryptophan Indole-Lyase  
Tree Number:   D08.811.520.224.800
Definition English:   An enzyme that catalyzes the conversion of L-tryptophan and water to indole, pyruvate, and ammonia. It is a pyridoxal-phosphate protein, requiring K+. It also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine, and other 3-substituted amino acids. (From Enzyme Nomenclature, 1992) EC 4.1.99.1. 
History Note English:   91(72); was see under LYASES 1972-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   14770 
Unique Identifier:   D014368 

Occurrence in VHL:
 

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