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C-ERBB-3 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Receptor, erbB-3
Descriptor
Spanish
:
Receptor erbB-3
Descriptor
Portuguese
:
Receptor erbB-3
Synonyms
English
:
c-erbB-3 Protein
erbB-3 Protein
HER-3 Proto-Oncogene Protein
Proto-Oncogene Protein erbB-3
Tree Number:
D08.811.913.696.620.682.725.400.175
D12.776.543.750.060.437
D12.776.543.750.750.400.360
D12.776.624.664.700.790
D23.101.840.721
Definition
English
:
A cell surface protein-tyrosine kinase receptor that is specific for
NEUREGULINS
. It has extensive homology to and can heterodimerize with the EGF Receptor (RECEPTOR,
EPIDERMAL GROWTH FACTOR
) and the erbB-2 receptor (RECEPTOR, ERBB-2). Overexpression of the erbB-3 receptor is associated with tumorigenesis.
History Note
English
:
2000; use RECEPTOR, ERBB-3 (NM) 1990-1999
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34452
Unique Identifier:
D020893
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS