Search on: FPS PROTO-ONCOGENE PROTEIN 
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Descriptor English:   Proto-Oncogene Proteins c-fes 
Descriptor Spanish:   Proteínas Proto-Oncogénicas c-fes 
Descriptor Portuguese:   Proteínas Proto-Oncogênicas c-fes 
Synonyms English:   c-fes Proteins
fes Proto-Oncogene Proteins
fps Proto-Oncogene Protein  
Tree Number:   D08.811.913.696.620.682.725.300
D12.776.624.664.700.177
Definition English:   Proto-oncogene proteins fes are protein-tyrosine kinases with a central SH2 DOMAIN. It has been implicated in SIGNAL TRANSDUCTION PATHWAYS for CELL DIFFERENTIATION of a variety of cell types including MYELOID PROGENITOR CELLS. Fes proto-oncogene proteins also bind TUBULIN and promote MICROTUBULE assembly. 
History Note English:   2006(1986) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50731 
Unique Identifier:   D051578 

Occurrence in VHL: 		 

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