Search on: GRNA 
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Descriptor English:   RNA, Guide 
Descriptor Spanish:   ARN Guia 
Descriptor Portuguese:   RNA Guia 
Synonyms English:   gRNA
Guide RNA  
Tree Number:   D13.444.735.790.552.625
Definition English:   Small kinetoplastid mitochondrial RNA that plays a major role in RNA EDITING. These molecules form perfect hybrids with edited mRNA sequences and possess nucleotide sequences at their 5'-ends that are complementary to the sequences of the mRNA's immediately downstream of the pre-edited regions. 
Indexing Annotation English:   plays a major role in RNA EDITING; DF: note short X ref
See Related English:   RNA Editing
 
History Note English:   93; was GUIDE RNA (NM) 1990-92 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30530 
Unique Identifier:   D017394 

Occurrence in VHL:
 

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