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DeCS
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Descriptor English:
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Receptor, erbB-2
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Descriptor Spanish:
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Receptor erbB-2
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Descriptor Portuguese:
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Receptor erbB-2
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Synonyms English:
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c-erbB-2 Protein
erbB-2 Proto-Oncogene Protein
erbB-2 Receptor Protein-Tyrosine Kinase
neu Proto-Oncogene Protein
neu Receptor
HER-2 Proto-Oncogene Protein
Proto-Oncogene Protein p185(neu)
Proto-Oncogene Protein HER-2
Receptor, neu
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Tree Number:
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D08.811.913.696.620.682.725.400.150
D12.776.543.750.060.374
D12.776.543.750.750.400.350
D12.776.624.664.700.642
D23.101.840.642
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Definition English:
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A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members. |
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See Related English:
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Genes, erbB-2
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History Note English:
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2000(1995); use RECEPTOR, ERBB-2 (NM) 1985-1994
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Allowable Qualifiers English:
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Record Number:
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32062
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Unique Identifier:
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D018719
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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