Search on: TETRASPANINS 
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Descriptor English:   Tetraspanins 
Descriptor Spanish:   Tetraspaninas 
Descriptor Portuguese:   Tetraspaninas 
Tree Number:   D12.776.543.982
Definition English:   A large superfamily of cell surface membrane proteins characterized by their four transmembrane domains. They play a role in a variety of processes such as cellular adhesion and motility. They may be involved in the organization of cell surface MEMBRANE MICRODOMAINS that regulate the activation of LEUKOCYTES. 
Indexing Annotation English:   general or unspecified; prefer specifics
History Note English:   2012 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   54638 
Unique Identifier:   D059470 

Occurrence in VHL:
 

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