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CHLORIMIPRAMINE
Descriptors Found:
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DeCS
Descriptor
English
:
Clomipramine
Descriptor
Spanish
:
Clomipramina
Descriptor
Portuguese
:
Clomipramina
Synonyms
English
:
Chlorimipramine
Tree Number:
D03.494.240.194
Definition
English
:
A tricyclic antidepressant
similar
to
IMIPRAMINE
that selectively inhibits the uptake of
serotonin
in the
brain
. It is readily absorbed from the
gastrointestinal tract
and demethylated in the
liver
to form its primary active metabolite, desmethylclomipramine.
Pharmacological Action:
Antidepressive Agents, Tricyclic
Serotonin Uptake Inhibitors
History Note
English
:
80(75); was CHLORIMIPRAMINE see under DIBENZAZEPINES 1968-79
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
3022
Unique Identifier:
D002997
Occurrence in VHL
:
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DeCS
CID-10
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