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CLONAL DELETION
Descriptors Found:
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DeCS
Descriptor
English
:
Clonal Deletion
Descriptor
Spanish
:
Supresión Clonal
Descriptor
Portuguese
:
Deleção Clonal
Synonyms
English
:
Clonal Abortion
Tree Number:
G12.425.746.425.120
Definition
English
:
Removal, via
CELL DEATH
, of immature
lymphocytes
that interact with
antigens
during maturation. For
T-lymphocytes
this occurs in the thymus and ensures that mature
T-lymphocytes
are self tolerant.
B-lymphocytes
may also undergo
clonal deletion.
Indexing Annotation
English
:
a form of
immune tolerance
See Related
English
:
Apoptosis
History Note
English
:
94
Allowable Qualifiers
English
:
DE
drug effects
ES
ethics
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
31557
Unique Identifier:
D017637
Occurrence in VHL
:
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CID-10
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