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FIBROBLAST GROWTH FACTORS
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DeCS
Descriptor
English
:
Fibroblast Growth Factors
Descriptor
Spanish
:
Factores de Crecimiento de Fibroblastos
Descriptor
Portuguese
:
Fatores de Crescimento de Fibroblastos
Tree Number:
D12.644.276.624
D12.776.467.624
D23.529.624
Definition
English
:
A
family
of small polypeptide
growth
factors that share several common features including a strong affinity for
HEPARIN
, and a central barrel-shaped core region of 140
amino acids
that is highly homologous between
family
members. Although originally studied as
proteins
that stimulate the
growth
of
fibroblasts
this distinction is no longer a requirement for membership in the fibroblast
growth
factor
family.
See Related
English
:
Receptors, Fibroblast Growth Factor
History Note
English
:
2001(1984)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
5481
Unique Identifier:
D005346
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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