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GENES, IMMUNOGLOBULIN
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DeCS
Descriptor
English
:
Genes, Immunoglobulin
Descriptor
Spanish
:
Genes de Inmunoglobulinas
Descriptor
Portuguese
:
Genes de Imunoglobulinas
Synonyms
English
:
Genes, Ig
Immunoglobulin Genes
Tree Number:
G05.360.340.024.340.335
G12.500.299
Definition
English
:
Genes
encoding the different subunits of the
IMMUNOGLOBULINS
, for example the IMMUNOGLOBULIN
LIGHT
CHAIN
GENES
and the IMMUNOGLOBULIN HEAVY CHAIN
GENES
. The heavy and
light
immunoglobulin
genes
are present as gene segments in the germline
cells
. The completed
genes
are created when the segments are shuffled and assembled (B-LYMPHOCYTE
GENE REARRANGEMENT
) during B-LYMPHOCYTE maturation. The gene segments of the human
light
and heavy chain germline
genes
are symbolized V (variable), J (joining) and C (constant). The heavy chain germline
genes
have an additional segment D (diversity).
See Related
English
:
Immunogenetics
Immunoglobulin Allotypes
Immunoglobulin Subunits
Immunoglobulins
History Note
English
:
88
Allowable Qualifiers
English
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
22903
Unique Identifier:
D005803
Occurrence in VHL
:
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