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NATRIURETIC PEPTIDE, C-TYPE
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DeCS
Descriptor
English
:
Natriuretic Peptide, C-Type
Descriptor
Spanish
:
Péptido Natriurético Tipo-C
Descriptor
Portuguese
:
Peptídeo Natriurético Tipo C
Synonyms
English
:
C-Type Natriuretic Peptide
Tree Number:
D06.472.699.584.750
D12.644.548.585.750
Definition
English
:
A PEPTIDE of 22
amino acids
, derived mainly from
cells
of VASCULAR
ENDOTHELIUM
. It is also found in the
BRAIN
, major
endocrine glands
, and other
tissues
. It shares structural homology with
ATRIAL NATRIURETIC FACTOR
. It has vasorelaxant activity thus is important in the regulation of vascular tone and
blood
flow. Several high
molecular weight
forms
containing the 22
amino acids
have been identified.
Pharmacological Action:
Natriuretic Agents
History Note
English
:
99; use C-TYPE NATRIURETIC PEPTIDE (NM) 1990-98
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
33835
Unique Identifier:
D020098
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS