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RENIN
Descriptors Found:
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DeCS
Descriptor
English
:
Renin
Descriptor
Spanish
:
Renina
Descriptor
Portuguese
:
Renina
Synonyms
English
:
Angiotensin-Forming Enzyme
Angiotensinogenase
Tree Number:
D08.811.277.656.074.500.780
D08.811.277.656.300.048.780
D08.811.277.656.837.750
Definition
English
:
A highly specific (Leu-Leu) endopeptidase that generates
ANGIOTENSIN I
from its precursor
ANGIOTENSINOGEN
, leading to a cascade of reactions which elevate
BLOOD PRESSURE
and increase
sodium
retention by the
kidney
in the
RENIN-ANGIOTENSIN SYSTEM
. The enzyme was formerly listed as EC 3.4.99.19.
Indexing Annotation
English
:
do not confuse with RENNIN see
CHYMOSIN
History Note
English
:
1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29553
Unique Identifier:
D012083
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS