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ANGIOPOIETIN-1
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DeCS
Descriptor
English
:
Angiopoietin-1
Descriptor
Spanish
:
Angiopoyetina 1
Descriptor
Portuguese
:
Angiopoietina-1
Tree Number:
D12.644.276.100.100.100
D12.776.467.100.100.100
D23.529.100.100.100
Definition
English
:
The first to be discovered member of the angiopoietin
family
. It may play a
role
in increasing the sprouting and branching of
BLOOD VESSELS
.
Angiopoietin-1
specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of
angiopoietin-1
occur due to
ALTERNATIVE SPLICING
of its mRNA.
Indexing Annotation
English
:
see SCR for organism-specific terms
History Note
English
:
2004; use ANGIOPOIETIN-1 (NM) 1997-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
38238
Unique Identifier:
D042683
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS