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ANGIOSTATINS
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DeCS
Descriptor
English
:
Angiostatins
Descriptor
Spanish
:
Angiostatinas
Descriptor
Portuguese
:
Angiostatinas
Tree Number:
D08.622.610.500
D12.644.276.100.450.500
D12.776.124.790.223.580.500
D12.776.377.715.182.580.500
D12.776.467.100.450.500
D23.529.100.450.500
Definition
English
:
Circulating 38-kDa
proteins
that are internal
peptide fragments
of
PLASMINOGEN
. The name derives from the fact that they are potent
ANGIOGENESIS INHIBITORS
.
Angiostatins
contain four KRINGLE DOMAINS which are associated with their potent angiostatic activity.
Pharmacological Action:
Angiogenesis Inhibitors
Antineoplastic Agents
History Note
English
:
2004; use ANGIOSTATINS (NM) 1994-2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
38124
Unique Identifier:
D043168
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS