Search on: HEPARAN SULFATE PROTEOGLYCANS 
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Descriptor English:   Heparan Sulfate Proteoglycans 
Descriptor Spanish:   Proteoglicanos de Heparan Sulfato 
Descriptor Portuguese:   Proteoglicanas de Heparan Sulfato 
Synonyms English:   Heparan Sulfate Proteoglycan
HSPG  
Tree Number:   D09.698.373.425.500
D09.698.735.400
D12.776.395.650.350
Definition English:   Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32) 
Indexing Annotation English:   do not confuse with HEPARAN SULFATE see HEPARITIN SULFATE
History Note English:   2006(1982) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   33479 
Unique Identifier:   D019812 

Occurrence in VHL:
 

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