Search on: PEPTAIBOLS 
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Descriptor English:   Peptaibols 
Descriptor Spanish:   Peptaiboles 
Descriptor Portuguese:   Peptaibols 
Synonyms English:   Alamethicins
Antiamoebins
Chrysospermins
Culicinins
Zervamicins  
Tree Number:   D12.644.504
Definition English:   A group of peptides characterized by length of 1-2 dozen residues with a high proportion of them being non-proteinogenic, notably alpha-aminoisobutyric acid (Aib) and isovaline, and have a C-terminal amino alcohol and N terminal alkyl group. They are found in FUNGI and some are ANTI-INFECTIVE AGENTS. They form channels or pores in target organisms. The term is a contraction of peptide-Aib-alcohol. 
History Note English:   2008; for EMERIMICINS use PEPTIDES 1977-2007 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   52785 
Unique Identifier:   D054848 

Occurrence in VHL:
 

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