Search on: ROTAXANES 
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Descriptor English:   Rotaxanes 
Descriptor Spanish:   Rotaxanos 
Descriptor Portuguese:   Rotaxanos 
Synonyms English:   Polyrotaxanes
Pseudorotaxanes  
Tree Number:   D02.825
Definition English:   Complex compounds in which a dumbbell shaped molecule is encircled by a macrocycle. They are named after rota (wheel) and axis (axle). Notation with a prefix is used to indicate the number of interlocked components. They have potential use in NANOTECHNOLOGY. Rotaxanes have been made with CYCLODEXTRINS and CYCLIC ETHERS. 
Indexing Annotation English:   coord with specific Cat D chemical structure term if pertinent; TAXANES is also available
See Related English:   Catenanes
 
History Note English:   2004 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DU diagnostic use
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   38085 
Unique Identifier:   D043862 

Occurrence in VHL:
 

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