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IONOPHORES
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DeCS
Descriptor
English
:
Ionophores
Descriptor
Spanish
:
Ionóforos
Descriptor
Portuguese
:
Ionóforos
Tree Number:
D27.505.519.562.374
D27.720.395
Definition
English
:
Chemical agents that increase the
permeability
of biological or artificial lipid
membranes
to specific
ions
. Most
ionophores
are relatively small organic molecules that act as mobile carriers within
membranes
or coalesce to form ion permeable channels across
membranes
. Many are antibiotics, and many act as
uncoupling agents
by short-circuiting the proton
gradient
across
mitochondrial membranes.
See Related
English
:
Cell Membrane Permeability
History Note
English
:
76
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
7644
Unique Identifier:
D007476
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS